This training is useful in giving me a firm foundation to acquire knowledge as a basis for future study and research activities,
and developing a logical and structural thinking mentality.
Master in Biostatistics
Hasselt University; 5 oktober 1999
Grade: magna cum laude
“Analysis of longitudinal, ordinal, categorical, quality of life data with dropout.“
Promotor: MSc D Curran; Co-promotors: MSc L Collette and Prof Dr G Molenberghs
The extensive training in biostatistics gives me the opportunity to translate a purely mathematical background into a practical social engagement.
Project-driven group assignments during the training are useful in developing skills to enhance team working.
The apprenticeship is enriching and is a first real exposure to the business community.
The nature of the student population – the majority were VLIR students from developing countries (this is: in Belgium with a Flemish Inter-university Board grant) – is extremely stimulating to adopt a positive international attitude and mentality.
II.2. Study background section B: Additional Study Certificates(a selection)
Diploma or certificate
IFRES 6 (séance de base)
Un guide pour l’enseignant, un guide pour l’étudiant: l’engagement pédagogique
Dispensation (tenue compte de ma formation de communication WECOM)
Biostatistical center de K.U.Leuven, LUC et university Gent (Belgium)
Workshop: Statistical analysis of discrete structures
Institut für Statistik Munich (Germany)
Multivariate Statistics in Practice
Groningen University (the Netherlands)
Computerintensive Methods in Statistics; Density Estimation, Smoothing in a S+ Environment
Hasselt University Belgium)
During the period 1997-1999 the emphasis mainly lies on gaining in-depth scientific biostatistics knowledge. Persistent training is necessary to surpass a simple executive function as a biostatistician. It enables me to closely follow the trends and evolutions in my discipline and to carry out creative and innovative scientific work.
This resulted, from 2000 onwards, in a period of self–study. I am feeling scientifically well-prepared to successfully start methodological research in biostatistics. Intense focus within this discipline has the risk of becoming alienated with other disciplines. That is why I choose for a doctoral training beyond the frontiers of pure statistics. For the aforementioned reason I also take a training in scientific communication.
The invitation to work at the Harvard School of Public Health 2003-2005) as a post-doctoral fellow allows me to make most of my chances to expand my work area. The vivid team spirit, the scientific discussions, enriched personal scientific research lead to a publication in Nature Genetics, despite the methodological nature of its content. At Harvard I also get the opportunity to expand my knowledge in non-statistics disciplines: biotechnology project management.
From 2006 onwards, the emphasis temporarily is on exploring and mapping new trends and evolutions in Europe, and on proposal drafting and writing. This focus, rather than carrying out pure methodological research to the extreme, is due to my 50% commitment as a project manager for the Ghent University to the European Network of Excellence GA2LEN (www.ga2len.com) up until the end of 2007.
2008 is the start of a bioinformatics tenure track position at the university of Liège. As the only statistician at the department of Electrical Engineering and Computer Science (Montefiore Institute) I formulate the mission to introduce statistical genetics and to start up a multi-disciplinary group that can make significant contributions to disentangle the genetics of complex diseases.
II.3. Study background section C: In case of a doctorate or special doctorate
PhD in Exact Sciences: Mathematics
Ghent University; 21 May 1996
Grade: summa cum laude
“Non-spherical buildings of rank 3.”
Promotor: Prof Dr H Van Maldeghem
Van Maldeghem H, Van Steen K (1999) Characterizations by Automorphism Groups of Some Rank 3 Buildings IV. Hyperbolic p-adic Moufang Buildings of Rank 3, Geometriae Dedicata 75: 115-122.
Van Steen K (1999) Characterizations by Automorphism Groups of Some Rank 3 Buildings III. Moufang-Like Conditions, Geometriae Dedicata 74: 225-240.
Van Maldeghem H, Van Steen K (1999) Characterizations by Automorphism Groups of Some Rank 3 Buildings II. A Half Strongly-Transitive Locally Finite Triangle Building is a Bruhat-Tits Builing, Geometriae Dedicata 74: 113-133.
Van Maldeghem H, Van Steen K (1998) Characterizations by Automorphism Groups of Some Rank 3 Buildings I. Some Properties of Half Strongly-Transitive Triangle Buildings, Geometriae Dedicata 73: 119-142
From a scientific viewpoint the study of fundamental mathematics at this level is a good basis for study and research work in other specialties.
During my research years in fundamental mathematics I considered it a challenge to convey abstract concepts in a teachable and exciting way to a varied audience. During symposia and workshops it becomes clear that communicative skills are essential in building out a career, independently of the discipline or type of work floor. Under the leadership of my promotor in those days, Prof Dr H Van Maldeghem, the first building stones are laid to canalize and further develop skills in communication.
The preparations for my first doctoral degree have accentuated my sense of analysis and synthesis, and are essential to nourish an independent and critical attitude.
“Genomic screening methodology for common diseases and complex traits -
Multiplicity and missingness: a statistical hurdle?”
Promotor: Prof Dr G Molenberghs; Co-promotor: Prof Dr NM Laird
Van Steen K, Laird NM, Markel P, Molenberghs G (2006) Approaches to handle incomplete data in family-based association testing. Ann Hum Genet 71: 141-151.
Van Steen K, Mcqueen MB, Herbert A, Raby B, Lyon H, Demeo DL, Murphy A, Su J, Datta S, Rosenow C, Christman M, Silverman Ek, Laird NM, Weiss St, Lange C (2005) Genomic screening and replication using the same data set in family-based association testing, Nature Genetics 37 (7) 683 – 691.
Van Steen K, Lange C (2005) PBAT: a comprehensive software package for genome-wide association analysis of complex familybased studies (Invited submission) Journal of Human Genomics 2 (1): 1-3.
Van Steen K, Tahri N, Molenberghs G (2004) Introducing the multivariate Dale model in population based genetic association studies, Biometrical Journal 46 (2):187-202.
An important part of this thesis is the result of my work at the Harvard School of Public Health as a post-doctoral fellow. At this school I am made aware of different English writing styles (European versus non-European) and am given useful comments on increasing the success rate of publications in American and non-American journals. I learn that adopting the correct conventions, etiquette and writing style can severely increase the rate of accepted project proposals.
A publication is not a private affair. Every manuscript is read by some internal specialists, heavily discussed upon with the authors, provided with comments to increase the value of the publication and only then released for submission in a scientific journal. Corporate thinking brought into practice …
A copy of diplomas and obtained certificates can be obtained upon request.