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Part I: Personalia First Name: Kristel Place of birth, Date: Dendermonde, 3 June 1969 Address

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Part I: Personalia First Name: Kristel Place of birth, Date: Dendermonde, 3 June 1969 Address



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Part I: Personalia

First Name: Kristel
Place of birth, Date: Dendermonde, 3 June 1969
Address: Krijgsbaan 147, D – 9140 Temse
Residence: see address
Contact information:
Phone: +32 (0)4 366 2692 (work)

E-mail: kristel.vansteen@ulg.ac.be


Part II: Study background
II.1. Study background section A: Obtained master degrees



  1. Diploma 1:

Master in Exact Sciences; Mathematics

Ghent University; 28 June 1991

Grade: summa cum laude


Thesis:
“Inleiding tot de gebouwentheorie.”

Promotor: Prof Dr H Van Maldeghem


Detailed information:


  • This training is useful in giving me a firm foundation to acquire knowledge as a basis for future study and research activities,

  • and developing a logical and structural thinking mentality.



  1. Diploma 2:

Master in Biostatistics

Hasselt University; 5 oktober 1999

Grade: magna cum laude


Thesis:
“Analysis of longitudinal, ordinal, categorical, quality of life data with dropout.“

Promotor: MSc D Curran; Co-promotors: MSc L Collette and Prof Dr G Molenberghs


Detailed information:


  • The extensive training in biostatistics gives me the opportunity to translate a purely mathematical background into a practical social engagement.

  • Project-driven group assignments during the training are useful in developing skills to enhance team working.

  • The apprenticeship is enriching and is a first real exposure to the business community.

  • The nature of the student population – the majority were VLIR students from developing countries (this is: in Belgium with a Flemish Inter-university Board grant) – is extremely stimulating to adopt a positive international attitude and mentality.


II.2. Study background section B: Additional Study Certificates (a selection)



Diploma or certificate

grade

university

Year

IFRES 6 (séance de base)

Un guide pour l’enseignant, un guide pour l’étudiant: l’engagement pédagogique






ULg (Belgium)

2010

IFRES 5

Dispensation (tenue compte de ma formation de communication WECOM)






ULg (Belgium)




IFRES 4

Organisation et évaluation des stages






ULg (Belgium)

2010

IFRES 3

Le titurat pour l’apprentissage par problems et en petits groupes






ULg (Belgium)

2010

IFRES 2

Introductio générale au PBLet au rôlede tuteur






ULg (Belgium)

2010

IFRES 1

Construction et gestion qualité de teste






ULg (Belgium)

2009

Statistical analysis of Networks

Certificate

UCL (Belgium)

2009

Cours : Français




Nationale Handels Academie Antwerp (Belgium)

2008

Continuing medical education: post genome respiratory epidemiology II: an interdisciplinary challenge

Certificate

Cernay-la-Ville (France)

2008

Workshop: Statistical analysis of genetic data in families

Certificate

FaBeR – KUL, (Belgium)

2008

FAMHAP – haplotype frequency estimation and association analysis

Certificate

Rheinische Friedrich-Wilhelms-Universitaet, Bonn (Germany)

2008

Good practice in DNA micro-array analysis

Certificate

Klinikum Großhadern, Munich (Germany)

2007

Erasmus Summer Program; Modules

Genetic epidemiology of complex diseases, Introduction to genomics en

Searching genes of complex disorders


Certificate

Erasmus Medical Centre Rotterdam (the Netherlands)

2006

SAS JMP genetics course

Certificate

Department of Cardiovascular Diseases – KUL (Belgium)

2006

S.A.G.E. course: statistical analysis for genetic epidemiology

Certificate

Department of Cardiovascular Diseases – Catholic University Leuven (Belgium)

2006

37th International training workshop on the use of GelCompar II and Bionumerics

Certificate

Applied Maths headquarters in Sint-Martens-Latem (Belgium)

2006

Doctoral Training: medical science


Certificate

Antwerp University

(Belgium)



2005

Biotechnology Project Management


A+

Harvard Extension School – Massachusetts Biotechnology Council (USA)

2005

Short course: Mathematical approaches to the analysis of complex phenotypes

Certificate

The Jackson Laboratory Bar Harbor – Main (USA)

2003

Short course: Bayesian hierarchical modelling using WinBUGS, IBConf

Certificate

Universität Freiburg (Germany)

2002

Advances in population-based studies of complex genetic disorders

Certificate

Erasmus Medical Centre Rotterdam (the Netherlands)

2001

Course: module 2: Bio-informatics

Certificate

ICES University Ghent (Belgium)

2001

Course: module 1: Bio-informatics

Certificate

ICES University Ghent (Belgium)

2001

WECOM: training in scientific communication: written communication


Certificate

Limburg University Centre Hasselt

(Belgium)



2001

WECOM: training in scientific communication: oral communication


Certificate

Limburg University Centre

(Belgium)



2001

Advances in population-based studies of complex genetic disorders

Certificate

Erasmus Medical Centre Rotterdam (the Netherlands)

2001

Course: Handling Non-response

Certificate

ESRC university Southampton (United Kingdom)

2000

Workshop: Statistical Inference

Certificate

University Hasselt (Belgium)

2000

Workshop sensitivity analysis for incomplete data

Certificate

Biostatistical center de K.U.Leuven, LUC et university Gent (Belgium)

2000

Workshop: Statistical analysis of discrete structures

Certificate

Institut für Statistik Munich (Germany)

2000

Multivariate Statistics in Practice

Certificate

Groningen University (the Netherlands)

1997

Computerintensive Methods in Statistics; Density Estimation, Smoothing in a S+ Environment

18/20

Hasselt University Belgium)

1997



Detailed information


  • During the period 1997-1999 the emphasis mainly lies on gaining in-depth scientific biostatistics knowledge. Persistent training is necessary to surpass a simple executive function as a biostatistician. It enables me to closely follow the trends and evolutions in my discipline and to carry out creative and innovative scientific work.

  • This resulted, from 2000 onwards, in a period of self–study. I am feeling scientifically well-prepared to successfully start methodological research in biostatistics. Intense focus within this discipline has the risk of becoming alienated with other disciplines. That is why I choose for a doctoral training beyond the frontiers of pure statistics. For the aforementioned reason I also take a training in scientific communication.

  • The invitation to work at the Harvard School of Public Health 2003-2005) as a post-doctoral fellow allows me to make most of my chances to expand my work area. The vivid team spirit, the scientific discussions, enriched personal scientific research lead to a publication in Nature Genetics, despite the methodological nature of its content. At Harvard I also get the opportunity to expand my knowledge in non-statistics disciplines: biotechnology project management.

  • From 2006 onwards, the emphasis temporarily is on exploring and mapping new trends and evolutions in Europe, and on proposal drafting and writing. This focus, rather than carrying out pure methodological research to the extreme, is due to my 50% commitment as a project manager for the Ghent University to the European Network of Excellence GA2LEN (www.ga2len.com) up until the end of 2007.

  • 2008 is the start of a bioinformatics tenure track position at the university of Liège. As the only statistician at the department of Electrical Engineering and Computer Science (Montefiore Institute) I formulate the mission to introduce statistical genetics and to start up a multi-disciplinary group that can make significant contributions to disentangle the genetics of complex diseases.


II.3. Study background section C: In case of a doctorate or special doctorate


  1. Diploma 1:

PhD in Exact Sciences: Mathematics

Ghent University; 21 May 1996

Grade: summa cum laude


Thesis:
“Non-spherical buildings of rank 3.”

Promotor: Prof Dr H Van Maldeghem



Publications:


  • Van Maldeghem H, Van Steen K (1999) Characterizations by Automorphism Groups of Some Rank 3 Buildings IV. Hyperbolic p-adic Moufang Buildings of Rank 3, Geometriae Dedicata 75: 115-122.

  • Van Steen K (1999) Characterizations by Automorphism Groups of Some Rank 3 Buildings III. Moufang-Like Conditions, Geometriae Dedicata 74: 225-240.

  • Van Maldeghem H, Van Steen K (1999) Characterizations by Automorphism Groups of Some Rank 3 Buildings II. A Half Strongly-Transitive Locally Finite Triangle Building is a Bruhat-Tits Builing, Geometriae Dedicata 74: 113-133.

  • Van Maldeghem H, Van Steen K (1998) Characterizations by Automorphism Groups of Some Rank 3 Buildings I. Some Properties of Half Strongly-Transitive Triangle Buildings, Geometriae Dedicata 73: 119-142

  • Van Maldeghem H, Van Steen K (1997) Moufang Affine Buildings have Moufang Spherical Building at Infinity, Glasgow Math. J. 39: 237-241



Detailed information


  • From a scientific viewpoint the study of fundamental mathematics at this level is a good basis for study and research work in other specialties.

  • During my research years in fundamental mathematics I considered it a challenge to convey abstract concepts in a teachable and exciting way to a varied audience. During symposia and workshops it becomes clear that communicative skills are essential in building out a career, independently of the discipline or type of work floor. Under the leadership of my promotor in those days, Prof Dr H Van Maldeghem, the first building stones are laid to canalize and further develop skills in communication.

  • The preparations for my first doctoral degree have accentuated my sense of analysis and synthesis, and are essential to nourish an independent and critical attitude.




  1. Diploma 2:

PhD in medical sciences – biomedical science

Hasselt University / Maastricht University; 20 December 2005

Grade: not applicable


Thesis:

“Genomic screening methodology for common diseases and complex traits -

Multiplicity and missingness: a statistical hurdle?”

Promotor: Prof Dr G Molenberghs; Co-promotor: Prof Dr NM Laird



Publications


  • Van Steen K, Laird NM, Markel P, Molenberghs G (2006) Approaches to handle incomplete data in family-based association testing. Ann Hum Genet 71: 141-151.

  • Van Steen K, Mcqueen MB, Herbert A, Raby B, Lyon H, Demeo DL, Murphy A, Su J, Datta S, Rosenow C, Christman M, Silverman Ek, Laird NM, Weiss St, Lange C (2005) Genomic screening and replication using the same data set in family-based association testing, Nature Genetics 37 (7) 683 – 691.

  • Van Steen K, Lange C (2005) PBAT: a comprehensive software package for genome-wide association analysis of complex family­based studies (Invited submission) Journal of Human Genomics 2 (1): 1-3.

  • Van Steen K, Tahri N, Molenberghs G (2004) Introducing the multivariate Dale model in population based genetic association studies, Biometrical Journal 46 (2):187-202.



Detailed information


  • An important part of this thesis is the result of my work at the Harvard School of Public Health as a post-doctoral fellow. At this school I am made aware of different English writing styles (European versus non-European) and am given useful comments on increasing the success rate of publications in American and non-American journals. I learn that adopting the correct conventions, etiquette and writing style can severely increase the rate of accepted project proposals.

  • A publication is not a private affair. Every manuscript is read by some internal specialists, heavily discussed upon with the authors, provided with comments to increase the value of the publication and only then released for submission in a scientific journal. Corporate thinking brought into practice …


A copy of diplomas and obtained certificates can be obtained upon request.

Part III: Knowledge and competences in a professional context
III.1. My curriculum
Overview:


Identification employer

Start date

End date

Position

Full time/ part-time %

University of Liège – Dept of electrical engineering and computer science

1/1/2008

-

Associate Professor

100

Catholic University of Leuven – Dept of Human Genetics

1/5/2008

30/9/2014

(honorary) guest-professor

10

Ghent University – Dept of Medical Genetics

1/10/2008

30/9/2011

(honorary) guest-professor

5

Ghent University – Dept ORL

1/2/2008

30/9/2011

(honorary) post-doctoral researcher

10


Univeritair Ziekenhuis UZ Ghent;

De Pintelaan 185, 5B2, 9000 Ghent



1/1/2006

31/12/2007

Post-doctoral scientific researcher (status: expert) – Project Manager GA2LEN Ghent University

50

Ghent University – Dept of applied mathematics and computer science

1/1/2006

31/12/2007

Guest Professor

50

StepGen cvba

26/1/2006

31/1/2010

Co-founder and scientific director




Ghent University – FP6 project GA2LEN

15/6/2005

31/12/2005

Post-doctoral scientific collaborator – Project Manager GA2LEN Ghent University

100

Hasselt University - Censtat

1/9/2003

present

(honorary) scientific collaborator




Harvard School of Public Health – Department of Biostatistics,

Boston MA 02115, USA



5/5/2003

31/5/2005

Post-doctoral fellow researcher on statistical genetics

100

Hasselt University (LUC – Censtat)

1/9/1999

31/5/2003

Post-doctoral researcher

100

Hasselt University (LUC – Censtat)

16/5/1999

31/8/1999

Scientific researcher

100

E.O.R.T.C (Quality of Life Unit) – Avenue Mounier 83, 1200 Brussel

16/11/1998

15/5/1999

Fellow statistician

100

Ghent University

1/9/1994

1/2/1992


31/1/1998

31/8/1994



Assistant Geometry

100

50


III.2. Situating the most important evolutions in my knowledge acquisition related to professional activities mentioned in III.1.



  1. Know-how 1: Logical thinking



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  • II.1. Study background section A: Obtained master degrees Diploma 1
  • II.2. Study background section B: Additional Study Certificates
  • II.3. Study background section C: In case of a doctorate or special doctorate Diploma 1
  • Van Steen K
  • A copy of diplomas and obtained certificates can be obtained upon request. Part III: Knowledge and competences in a professional context III.1. My curriculum
  • Identification employer Start date End date Position
  • Know-how 1: Logical thinking

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