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Part I: Personalia First Name: Kristel Place of birth, Date: Dendermonde, 3 June 1969 Address

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Part I: Personalia First Name: Kristel Place of birth, Date: Dendermonde, 3 June 1969 Address



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Legend: italic = future conferences with scheduled participation.



  1. Detailed information about scientific announcements




Announcements at international conferences and symposia
Publications other than articles


  • Arijs I, Van Lommel L, De Hertogh G, Machiels K, Lemaire K, Van Steen K, Van Assche G, Vermeire S, Schuit F, Rutgeerts P (2011) Mucosal gene expression profiling differentiates early from late ileal Crohn’s disease (submitted for DDW 2011) Gastroenterology

  • Cleynen I, Artieda M, Szczypiorska M, Verspaget WH, Lakatos LP, Seibold F, Ahmad T, Weersma KR, Müller S, Tordai A, Hommes WD, Parnell K, Wijmenga C, Van Steen K, Rutgeerts P, Lottaz D, Vermeire S (2011) The protease genes CYLD and USP40 are associated with Crohn’s disease: results from a European Consortium Gastroenterology

  • De Greef I, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paquot I, Alliet P, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier JF, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K, Veereman G (2011) Profile of Belgian Pediatric Crohn Disease (CD) Patients: Presentation and Diagnostic Features (submitted for 6th Congress of ECCO - Inflammatory Bowel Diseases 2011) Journal of Crohn’s and Colitis

  • De Greef I, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paquot I, Alliet P, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier JF, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K, Veereman G (2011) Profile of Belgian Pediatric Crohn Disease (CD) Patients: Presentation and Diagnostic Features (submitted for DDW 2011) Gastroenterology

  • De Greef I, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paquot I, Alliet P, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier JF, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K, Veereman G (2011) Profile of Belgian Pediatric Crohn Disease (CD) Patients: Associations between variables at diagnosis (submitted for 6th Congress of ECCO - Inflammatory Bowel Diseases 2011) Journal of Crohn’s and Colitis

  • De Greef I, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paquot I, Alliet P, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier JF, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K, Veereman G (2011) Profile of Belgian Pediatric Crohn Disease (CD) Patients: Associations between variables at diagnosis (submitted for DDW 2011) Gastroenterology

  • Drobne D, Bossuyt P, Breynaert C, Cattaert T, Vande Casteele N, Compernolle G, Juergens M, Ballet V, Cleynen I, Wollants WJ, Van Steen K, Gils A, Rutgeerts P, Vermeire S, Van Assche G (2011) Long term evolution and impact of immunomodulator co-treatment and withdrawal on infliximab trough levels in 223 patients with Crohn’s disease (submitted for 6th Congress of ECCO - Inflammatory Bowel Diseases 2011) Journal of Crohn’s and Colitis

  • Steinborn A, Beigel F, Breiteneicher S, Van Steen K, Schnitzler F, Göke B, Weidinger M, Brand S, Ochsenkühn T, Seiderer J (2011) Risk Of Malignancies In A Single Center Cohort Of IBD-Patients Treated with Immunosuppressives and Anti-TNF-antibodies (submitted for 6th Congress of ECCO - Inflammatory Bowel Diseases 2011) Journal of Crohn’s and Colitis

  • Steinborn A, Beigel F, Breiteneicher S, Van Steen K, Schnitzler F, Göke B, Weidinger M, Brand S, Ochsenkühn T, Seiderer J (2011) Risk Of Malignancies In A Single Center Cohort Of IBD-Patients Treated with Immunosuppressives and Anti-TNF-antibodies (submitted for DDW 2011) Gastroenterology




  • Arijs I, Quintens R, Lemaire K, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. (2010) Intestinal mucosal gene expression of endothelial cell adhesion molecules in patients with inflammatory bowel disease and the impact of infliximab therapy. Journal of Crohn’s and Colitis.

  • Arijs I, Quitens R, Lemaire K, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P (2010) The impact of infliximab therapy on intestinal mucosal gene expression of endothelial cell adhesion molecules in patients with inflammatory bowel disease. Gastoenterology 138 (5(Suppl I)): 677.

  • Arijs I, Quintens R, Lemaire K, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F and Rutgeerts P. (2010) Intestinal mucosal expression of matrix metalloproteinase and ADAM genes in patients with inflammatory bowel disease and the impact of infliximab therapy. Gastroenterology, 138 (5(suppl I)): 677.

  • Breynaert C, Ferrante F, Fidder H, Van Steen K, Noman M, Ballet V, Vermeire S, Rutgeerts P, Van Assche G (2010) Tolerability of shortened infliximab infusion times in patients with inflammatory bowel diseases: a single center cohort study – UEGW 2010 Gut

  • Cleynen I, Mahachie John J.M, Henckaerts L, Van Moerkercke W, Rutgeerts P.J, Van Steen K, and Vermeire S. (2010) Molecular Reclassification of Crohn’s Disease by cluster analysis of genetic variants. Gastroenterology.

  • Cleynen I, Mahachie John J.M, Henckaerts L, Van Moerkercke W, Rutgeerts P.J, Van Steen K, and Vermeire S. (2010) Molecular Reclassification of Crohn’s Disease by cluster analysis of genetic variants. Gut

  • Jürgens M, Mahachie John J, Van Steen K, Schnitzler F, Ballet V, Noman M, Hoffman I, Van Assche GA, Rutgeerts PJ, Vermeire S (2010) Kinetics of C-reactive Protein (CRP) Following Maintenance Infliximab Treatment in Crohn’s disease identifies profiles of patients with better outcome Journal of Crohn’s and Colitis.

  • Jürgens M, Mahachie John J, Van Steen K, Schnitzler F, Ballet V, Noman M, Hoffman I, Van Assche GA, Rutgeerts PJ and Vermeire S (2010) Kinetics of C-reactive Protein (CRP) following maintenance infliximab treatment in crohn’s disease identifies profiles of patients with better outcome. Gastroenterology 138 (5 (suppl I)): 686.

  • Mahachie John JM, Roll S, Lau S, Lødrup Carlsen KC, Carlsen KH, Kuehni C, Spycher B, Torrent M, Sunyer J, Chen CM , Heinrich J, Arshad SH, Roberts G, Gehring U, Kerkhof M, Wickman M, Kull I, Eller E, Bindslev-Jensen C, Kramer U, von Berg A, Wahn U, Van Steen K, and Keil T (2010) Longitudinal study of European birth cohorts on pet ownership up to age 10 years as a risk for childhood asthma - a GA²LEN project – European Respiratory journal. Supplement.




  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Quintens R, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P (2009) Colonic mucosal expression of barrier genes in patients with inflammatory bowel disease before and after first infliximab treatment. Journal of Crohn’s and Colitis 3 (1): 3.

  • Arijs I, Quintens R, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P (2009) The impact of infliximab therapy on colonic mucosal expression of barrier genes in patients with inflammatory bowel disease. Gastroenterology; 136: 1190.

  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Quintens R, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. (2009) TECK and MADCAM-1 mucosal expression in active IBD: the effect of infliximab therapy. Gastroenterology 136: 1180.

  • Arijs I, Lemaire K, Quintens R, Van Lommel L, Perrier C, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P (2009). The impact of infliximab therapy on intestinal mucosal expression of matrix metalloproteinase and ADAM genes in patients with inflammatory bowel disease. Gut

  • Cleynen I, Van Moerkercke W, Mahachie John JM, Rutgeerts P, Van Steen K and Vermeire S. (2009) Cluster analysis of genetic variants enables reclassification of Crohn’s disease at the molecular level. Gut.

  • Cleynen I, Mahachie John JM, Henckaerts L, Van Moerkercke W, Rutgeerts PJ, Van Steen K, and Vermeire. S (2009). Molecular Reclassification of Crohn’s Disease by cluster analysis of genetic variants. Gut

  • Cleynen I, Van Moerkercke W, Mahachie John JM, Rutgeerts P, Van Steen K and Vermeire S.(2009) Cluster analysis of genetic variants enables reclassification of Crohn’s disease at the molecular level. Gut

  • De Lobel L, De Meyer H, Thijs L, Kouznetsova T, Staessen J, Van Steen K.(2009) A Family-Based Association Test to Detect Gene-Gene Interactions in the Presence of Linkage. Genetic Epidemiology 33 (8): 771 A68.

  • Jürgens M, Schnitzler F, Van Steen K, Mahachie J, Ballet V, Noman M, Hoffman I, Van Assche G, Rutgeerts PJ, Vermeire S (2009) Predictive Value of C-Reactive Protein Level Changes On the Long Term Outcome of Infliximab in Crohn's Disease. Gastroenterology 136 (5): 171.

  • Jürgens M, Schnitzler F, Cleynen I, Fidder H, Van Steen K, Mahachie J, Ballet V, Noman M, Hoffman I, Van Assche GA, Rutgeerts PJ, Vermeire S (2009). Is CRP predictive for mucosal healing in CD patients under infliximab therapy? Gut




  • Arijs I, Lemaire K, Quintens R, Van Lommel L, Leemans P, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. (2008) Gene expression of antimicrobial peptides in colonic mucosa of patients with inflammatory bowel disease before and after first infliximab treatment. Gut 57 (Suppl. II): 102-A103 .

  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Ferrante M, Joossens M, Geboes K, Van Assche GA, Vermeire S, Schuit FC, Rutgeerts PJ (2008) Mucosal gene signatures to predict response to infliximab in patients with inflammatory bowel disease. Gastroenterology 134: 117.

  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Ferrante M, Joossens M, Geboes K, Van Assche G, Vermeire S, Schuit F, Rutgeerts P (2008) Mucosal gene signatures to predict response to infliximab in patients with inflammatory bowel disease. Journal of Crohn's and Colitis Supplements 2 (1): 64.

  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Quintens R, Lemaire K, Joossens M, Schuit F, Geboes K, Van Assche G, Vermeire S, Rutgeerts P. (2008) Microarray study of mucosal antimicrobial peptides in patients with inflammatory bowel disease before and after infliximab treatment. Journal of Crohn's and Colitis Supplements February 2008 2 (1): 60.

  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Quintens R, Lemaire K, Joossens M, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. (2008) Microarray study of mucosal antimicrobial peptides in patients with inflammatory bowel disease before and after first infliximab treatment. Gastroenterology 134: 2043 .

  • Arijs I, Quintens R, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. (2008) Effect of infliximab treatment on colonic mucosal gene expression profiles in patients with inflammatory bowel disease. Gut 57 (Suppl. II): A39 .

  • Cleynen I, Claes B, Nuytten H, Van Steen K, Henckaerts L, Fidder H, Noman M, Cuppens H, Lambrecht D, Rutgeerts P, Vermeire S. (2008) Development of psoriasiform skin lesions in IBD patients under anti-TNF therapy: a genetic link? Abstract Book of the American Society of Human Genetics 2008, 2053W.

  • De Lobel L, De Meyer H, Thijs L, Kouznetsova T, Staessen J, Van Steen K (2008) A Family-based Association Test for Quantitative Traits to Detect Gene-Gene Interactions. Genetic Epidemiology 32(7): 686-686

  • De Lobel L, De Meyer H, Baele G, Kogevinas M, Van Steen K. (2008) Alternative methods to detect gene-gene interactions. Abstract Book of the American Society of Human Genetics 2008, 2474F

  • Ferrante M, Vermeire S, Schitzler F, Noman M, Van Assche G, Arijs I, Joossens M, Cleynen I, Vermeulen N, Hoffman I, Van Steen K, Rutgeerts P. (2008) Long-term efficacy of infliximab and colectomy-free survival in outpatients with refractory ulcerative colitis. Journal of Crohn's and Colitis Supplements 2 (1): 3.

  • Henckaerts L, Cleynen I, Joossens M, Van Steen K, Claes K, Rutgeerts P, Vermeire S (2008) Genetic markers and the risk of complicated disease behaviour in Crohn's disease patients. Gastroenterology 134 (4): A349.

  • Joossens M, De Preter V, Van Steen K, Vermeulen N, Huys G, Verbeke K, Vandamme P, Rutgeerts P, Vermeire S (2008) Stability of gut microbiota over time in Crohn's disease patients compared to healthy relatives. Gastroenterology 134 (4): A653.

  • Joossens M, De Preter V, Van Steen K, Vermeulen N, Huys G, Verbeke K, Vandamme P, Rutgeerts P, Vermeire S. Stability Of Gut Microbiota Over Time In Crohn's Disease Patients Compared To Healthy Relatives. Journal of Crohn's and Colitis Supplements 2 (1): 94.

  • Van Steen K, Calle M, Urrea V, Malats N (2008) FAM-MDR: A flexible method of multifactor dimensionality reduction for high-order genetic interaction detection in related individuals. Abstract Book of the American Society of Human Genetics 2473F




  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P.(2007) Gene expression profiling to predict the response of infliximab in patients with UC. Gastroenterology 132(4): A-174 .

  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. (2007) Mucosal gene expression profiling to predict the response to infliximab in patients with ulcerative colitis. Gut 56 (Suppl. III): 19 (OP-G-86).

  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Schuit F, Geboes K, Van Assche G, Vermeire S, Rutgeerts P, Gene expression profiling to predict the response to infliximab in patients with ulcerative colititis. Journal of Crohn's and Colitis Supplements 1 (1): 34.

  • Efficace F, Bottomley A, Coens C, Van Steen K, Conroy T, Schoffski P, Schmoll H, Van Cutsem E, Köhne C-H (2007) Does a patient’s self-reported quality of life predict survival beyond key biomedical data in advanced colorectal cancer? (Eur J Cancer. 42 (1): 42-49). Erratum published in: Eur J Cancer , 43 (3): 633.

  • Henckaerts L, Verstreken I, Van Steen K, Vlietinck R, Rutgeerts P, and Vermeire S, (2007) Genetic markers and the risk of complicated disease behaviour in Crohn’s disease patients. Journal of Crohn's and Colitis Supplements March 2007, 1(1): 41-42).

  • Henckaerts L, Verstreken I, Van Steen K, Vlietinck R, Rutgeerts P, and Vermeire S, (2007) Genetic markers and the risk of complicated disease behaviour in Crohn’s disease patients Gut

  • Henckaerts L, Venstreken I, Van Steen K, Vlietinck R, Rutgeerts P, and Vermeire S. (2007) Genetic markers and risk of complicated disease behaviour in Crohn’s disease patients. Gastroenterology 132 (4 (Suppl. 2)): 17- A18.

  • Joossens M, De Preter V, Vanhoutte T, Van Steen K, Huys G, Verbeke K, Vandamme P, Rutgeerts P, Vermeire S (2007) Faecal bacterial molecular profiles of Crohn’s disease patients differ from their healthy relatives and matched healthy controls. Gut 56 (Suppl III): A5 .

  • Joossens M, Vanhoutte T, De Preter V, Van Steen K, Henckaerts L, Arijs I, Huys G, Verbeke K, Vandamme P, Rutgeerts P, Vermeire S. Faecal bacterial dgge profiles of Crohn's disease patients are different from those of their healthy first degree relatives and matched healthy controls. Gastroenterology 132 (4): 704-A704.

  • Joossens M, Vanhoutte T, De Preter V, Van Steen K, Henckaerts L, Huys G, Verbeke K, Vandamme P, Rutgeerts P, Vermeire S. (2007) Faecal bacterial dgee profiles of Crohn’s disease patients are different from those of their healthy first degree relatives and matched healthy controls. Journal of Crohn's and Colitis Supplements 1(1): 55.

  • Pierik M, Van Steen K, Joossens M, Rutgeerts PJ, and Vermeire S (2007) Mixed IBD families: A distinct entity within IBD. Gastroenterology 132 (4(Suppl 2)): 450-A450.

  • Roll S, Keil T, Eller E, Bindslev-Jensen C, Kraemer U, Chen C, von Berg A, Smit H, Wijga A, Carlsen KL, Carlsen K, Wickman M, Kull I, Mommers M, Thijs C, Forastiero F, Porta D, Fantin I, Bravi F, Van Steen K, Willich S, Wahn U, Lau S, Heinrich J (2007) Pet ownership in eight European cohorts – results of a GA2LEN initiative. Allergy 62 (Suppl 2): 67-67.




  • A. Bottomley, Efficace F, Stuppe R, Van Steen K, Coens C, Osoba , van Den Bent M, Mason W, Cairncross G, Eisenhauer E, Wong R, Villa S, Mirimanoff R, Reni M, Taphoorn MJ. A bootstrap model averaging technique to investigate the prognostic value for survival of quality of life information. Qual Life Res 14 (9): 2136, 2005 (abs. 1022).

  • Bottomley A, Smit E, Efficace F, Schramel F, Smit HJ, Gaafar R, Biesma B, Lianes P, Van Steen K, Coens C, Van Meerbeeck J. (2005) Non-small cell lung cancer and health-related quality of life (HRQOL): Is baseline HRQOL of prognostic value for survival? Qual Life Res 14 (9): 2050 (abs. 1013)

  • Bottomley A, Taphoorn M, Coens C, Osoba D, Van Steen K, Efficace F, van Den Bent M, Baumert B, Mason W, Stupp R. (2005) Predicting survival using health related quality of life scores in glioblastoma cancers: Findings from an international phase III randomised controlled trial. Journal of Clinical Oncology 23 (16S): 9601.

  • Celedon JC, Van Steen K, Lange C, Raby B, Tantisira K, Silverman EK, Weiss ST. (2005) Genetic predictors of asthma exacerbations among children in the childhood asthma management program. Abstract Book of the American Society of Human Genetics 2005, 1662

  • Efficace F, Bottomley A, Coens C, Van Steen K, Conroy T, Köhne CH, Schoffski P, Schmoll P, Van Cutsem E. On behalf of the EORTC Gastrointestinal Tract Cancer Group. (May, 2005). The value of patient-reported symptoms as prognostic factors for survival in advanced colorectal cancer. Journal of Clinical Oncology supplement 23 (165): 267 (abs.3585).

  • Efficace F, Bottomley A, Coens C, Van Steen K, Conroy T, Schöffski P, Schmoll H, Van Cutsem E, Köhne CH. ( 2005). The prognostic value of health related quality of life in colorectal cancer patients: A multivariate analysis using a bootstrap model-averaging approach. 12th Annual Conference of the International Society for Quality of Life Research, San Francisco, CA (USA). Quality of Life Research 14 (9): 2137 (abs.1030).

  • Lange C, Van Steen K, McQueen M, Herbert A, Raby B, Lyon H, DeMeo D, Murphy A, Su J, Datta S, Rosenow C, Christman M, Silverman EK, Weiss ST. Genomic screening and replication in one data set in family-based association testing. Abstract Book of the American Society of Human Genetics 2005, 2370

  • Mcqueen MB, Murphy A , Kraft P, Su J, Lazarus R, Laird NM, Lange C, Van Steen K (2005) Comparison of Linkage and Association Strategies for Quantitative Traits using the COGA Dataset. Genet. Epidemiol. 29 (Suppl. 1): 1-S9.

  • Mcqueen MB, Murphy A, Kraft P, Su J, Lazarus R, Laird NM, Lange C, Van Steen K (2005) Comparison of Linkage and Association Strategies for Quantitative Traits using the COGA Dataset, BMC Genet. 6 (Suppl 1): 96

  • Murphy A, Mcqueen MB, Su J, Kraft P, Lazarus R, Laird NM, Lange C, Van Steen K (2005) Genomic Screening in Family Based Association Testing, BMC Genet. 6 (Suppl 1): S115.

  • Van Steen K, McQueen MB, Herbert A, Rosenow C, Silverman EK, Laird NM, Weiss ST, Lange C. (2005) Genomic screening in family based association testing and the multiple testing problem. Genetic Epidemiology 28: 164.




  • Efficace F, Therasse P, Piccart M, Coens C, Van Steen K, Welnicka-Jaskiewicz M, Cufer T, Lichinitser M, Shepherd L, Bottomley A, (2004) Predicting survival with health-related quality of life scores in locally advanced breast cancer: results from an international randomized controlled trial. Journal of Clinical Oncology 23: 31 (abs.618).

  • Van Steen K, McQueen MB, Herbert A, Laird NM, Raby B, Lyon H, Su J, Datta S, Rosenow C, Silverman EK, Weiss ST, Lange C (2004). Genomic screening in family based association testing. Genetic Epidemiology 27, 300 A142.




  • Joossens S, Van Steen K, Vermeire SV, Reinisch W, Colombel JF, Rutgeerts P (2003) The value of serologic markers in indeterminate colitis: A prospective follow-up study - Reply. Gastroenterology 125: 999-1000.

  • Pierik M, Vermeire S, Van Steen K, Joosens S, Vlietinck R, Rutgeerts P (2003) TNF-alpha receptor 1 and 2 (TNFR1 and TNFR2) polymorphisms in IBD and their association with response to infliximab. Gut 52 (suppl IV):A205.

  • Pierik M, Vermeire S, Van Steen K, El Housni H, Deviere J, Rutgeerts P, Franchimont D, Deficient host-bacteria interaction in inflammatory bowel disease (IBD): the Toll-like receptor (TLR)-4 asp299gly polymorphisms is associated with Crohn’s disease (CD) and ulcerative colitis (UC). Gut 2003; 52 (supplIV): A36.

  • Vermeire S, Esters N, Pierik M, Claessens G, Joossens S, Vlietinck R, Van Steen K, and Rutgeerts P,(2003) Transmission of CARD15 (NOD2) variants in families with Crohns disease. Gastroenterology 124 (4(suppl I)): A368-368.




  • Bottomley A, Thomas K, Van Steen K, Flechtner H, Djulbegovic B (2002) A systematic review of the use of recombinant human erthropoietin (r-HuEPO) an its effects on quality of life (QOL) and fatigue in cancer patients. Journal of Clinical Oncology 21: 377a (A1504).

  • Jansen I, Van Steen K, Molenberghs G, De Wit M, Peeters M, (2002) Using word frequencies for testing the equivalence between two DNA sequences. Genetic Epidemiology 23: 287.

  • Van Steen K, Molenberghs G, Tahri N. (2002) The multivariate Dale model and genetic associations. Supplement to The American Journal of Human Genetics;71, 577.

  • Van Steen K, Molenberghs G, Tahri N, (2002) Merits of the multivariate Dale model in genetic association studies. Genetic Epidemiology; 23: 309.




  • Jansen I, Molenberghs G, Aerts M, Thijs H, Van Steen K, (2001) Analysis of binary data from a psychiatric study: a local influence approach. New Trends in Statistical Modelling, s.l,2001, p. 235-242.

  • Thijs H, Van Steen K, Molenberghs G, De Wit M, Peeters M, (2001) An equivalence test for comparing DNA sequences, Supplement to The American Journal of Human Genetics 2001; 69 (4): 451.

  • Van Steen K, Tahri N, Molenberghs G, (2001) Introduction of the multivariate Dale model in genetic association studies, Supplement to The American Journal of Human Genetics; 69(4): 1289 A403.



Abstracts – no publication information available


  • Cattaert T, Van Steen K (2011) The impact of genotyping error on power and type-I error of quantitative trait genetic association studies – EMGM 2011, London, United Kingdom

  • Cattaert T, Van Lishout F, Rial J, Van Steen K (2011) Comparison of MB-MDR to BOOST andRAPID for detecting epistasis in unrelated - 6th EMR-IBS, Crete, Greece

  • De Greef I, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paquot I, Alliet P, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier JF, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K, Veereman G (2011) Profile of Belgian Pediatric Crohn Disease (CD) Patients: Presentation and Diagnostic Features – BVK Brussels 2011

  • De Greef I, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paquot I, Alliet P, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier JF, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K, Veereman G (2011) Profile of Belgian Pediatric Crohn Disease (CD) Patients: Presentation and Diagnostic Features – ESPGHAN, Sorento 2011

  • De Greef I, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paquot I, Alliet P, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier JF, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K, Veereman G (2011) Profile of Belgian Pediatric Crohn Disease (CD) Patients: Associations between variables at diagnosis – BVK Brussels 2011

  • De Greef I, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paquot I, Alliet P, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier JF, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K, Veereman G (2011) Profile of Belgian Pediatric Crohn Disease (CD) Patients: Associations between variables at diagnosis – ESPGHAN, Sorento 2011

  • Gusareva E, Huyghe J, Van Steen K (2011) Genome-wide epistasis screening for asthma associated traits – submitted for ISM2011 / Joint Statistical Meetings, Miami Beach, Florida USA

  • Mahachie John JM, Cattaert T, Van Lishout F, Van Steen K (2011) A detailed view on model-based multifactor dimensionality reduction with quantitative traits for detecting gene-gene interactions: different ways of adjusting for lower-order effects - Human Genetics Meeting, Dubai, United Arab Emirates

  • Mahachie John JM, Cattaert T, Van Lishout F, Van Steen K (2011) A detailed view on model-based multifactor dimensionality reduction with quantitative traits for detecting gene-gene interactions: different ways of adjusting for lower-order effects – ESHG 2011, Amsterdam, the Netherlands

  • Van Steen K (2011) Got heritability lost in a world of interactions? - Human Genetics Meeting, Dubai, United Arab Emirates

  • Van Lishout F, Cattaert T, Mahachie John JM, Wehenkel L, Van Steen K (2011) A Memory Efficient Algorithm to Perform Multiple-Testing in Epistasis Screening- 6th EMR-IBS, Crete, Greece

  • Vieira M, Van Steen K, Salvatore S, Vandenplas Y Effects of domperidone on Qtc interval in infants. – ESPGHAN 2011




  • Cattaert T, De Lobel L, Van Steen K (2010) Using mixed models with a mixture of normal distributions for the random residual effect leads to a fast and powerful genomewide association test –25th International Biometric Conference IBC2010, Florianopolis, Brasil.

  • Cattaert T, Mahachie John JM, Van Lishout F, Van Steen K (2010) Alternative risk cell definitions based on ranking improve performance of model-based multifactor dimensionality reduction for epistasis detection –IGES 2010

  • Cattaert T, Mahachie John JM, Van Lishout F, Van Steen K (2010) Alternative risk cell definitions based on ranking improve performance of Model-Based Multifactor Dimensionality Reduction for epistasis detection – First edition of Capita Selecta in Complex Disease Analysis CSCDA2010

  • Cattaert T, Calle ML, Dudek SM, Mahachie John JM, Van Lishout F, Urrea V, Ritchie MD, Van Steen K (2010) A detailed view on several Model-Based Multifactor Dimensionality Reduction methods for detecting gene-gene interactions in case-control data in the absence and presence of noise – ECCB 2010, Ghent , Belgium

  • Cleynen I, Mahachie John JM, Henckaerts L, Van Moerkercke W, Rutgeerts P, Van Steen K, Vermeire S (2010) Molecular reclassification of Crohn’s disease by cluster analysis of genetic variants –First edition of Capita Selecta in Complex Disease Analysis CSCDA2010

  • De Lobel L, Thijs L, Kouznetsova T, Staessen J, Van Steen K (2010) A Family-based Association Test to Detect Gene-Gene Interactions in the Presence of Linkage –First edition of Capita Selecta in Complex Disease Analysis CSCDA2010

  • De Lobel L, Thijs L, Kouznetsova T, Staessen JA, Van Steen K (2010) A Family-Based Association Test to Detect Gene-Gene Interactions in the Presence of Linkage –25th International Biometric Conference IBC2010, Florianopolis, Brasil.

  • Haerynck F, Loeys B, Van Steen K, van Daele S, Schelstraete P, Rossau R, De Baets F (2010) Association of MASP3 and FCN2 gene polymorphisms with the age of onset of chronic Pseudomonas aeruginosa ( Pa ) - ECFS ( European Cystic fibrosis society ) congress- Valencia

  • Haerynck F, Loeys B, Van Steen K, van Daele S, Schelstraete P, Rossau R, De Baets F (2010) Association of MASP3 and FCN2 gene polymorphisms with the age of onset of chronic Pseudomonas aeruginosa ( Pa ) - ESID ( European Society for Immune deficiencies ) congress - Istanbul

  • Huyghe JR, Van Camp G, Van Steen K (2010) Elucidating the Molecular Etiology of Asthma using Genome-Wide Association Study Pathway Analysis. –First edition of Capita Selecta in Complex Disease Analysis –First edition of Capita Selecta in Complex Disease Analysis CSCDA2010

  • Mahachie John JM, Cattaert T, Van Lishout F, Van Steen K (2010) Model-Based Multifactor Dimensionality Reduction to detect epistasis for quantitative traits in the presence of error-free and noisy data – IGES 2010

  • Mahachie John JM, Cattaert T, Van Lishout F, Van Steen K (2010) A detailed view on model-based multifactor dimensionality reduction with quantitative traits for detecting gene-gene interactions: different ways of adjusting for lower-order effects –25th International Biometric Conference IBC2010, Florianopolis, Brasil.

  • Mahachie John JM, Cattaert T, Van Lishout F, Van Steen K (2010) A detailed view on model-based multifactor dimensionality reduction with quantitative traits for detecting gene-gene interactions: different ways of adjusting for lower-order effects. –First edition of Capita Selecta in Complex Disease Analysis CSCDA2010

  • Savenije OEM, Mahachie John JM, Kerkhof M, Postma DS, Van Steen K & Koppelman GH (2010) Genetic epistasis in the IL1RL1 pathway and wheezing phenotypes: multinomial MB-MDR analyses–First edition of Capita Selecta in Complex Disease Analysis CSCDA2010 (responsible author).




  • Cattaert T, Urrea V, Calle ML, De Wit V, Mahachie John JM, Van Steen K (2009) Unified framework for epistasis detection in (un)-relateds – 5th conference of the Eastern Mediterranean Region of the Internation Biometric Society IBS 2009

  • Cattaert T, Mahachie John JM, Van Steen K (2009). Selecting multiple epistatic models using MB-MDR. Abstract Book of the Annual meeting of the American Society of Human Genetics 2009,1848

  • De Wit V, Vermeirssen V, Huyghe J, Van de Peer Y, Van Steen K (2009) Epistasis detection using MB-MDR, guided by prior biological knowledge –IGES 2009




  • Perez-Alvarez N, Konings P, Van Steen K, Nadia T. (2008) Analysis of an outcome beyond a detection limit: Application to HIV RNA data – IBC 2008

  • Van Der Gucht B, Konings P, Rooms J, Van Wanzeele F, Pelgrom J, Verhofstede C, Van Steen K, Blot S, Vandekerckhove L, Vogelaers D. (2008) High success rates in virologic suppression in initial HAART regimens: a tool for benchmarking quality of HIV care? – AIDS 2008




  • Kogevinas M, Castro-Giner F, de Cid R, Jarvis D, Van Steen K, Anto J-M, Wjst M and the ECRHS study group. (2007) Replication of positionally cloned asthma genes in an international population-based cohort study (ECRHS-II). – ERS 2007, Stockholm, Sweden, 17-19 September 2007.

  • Willemarck N, Van Poucke M, Van Steen K, Maes S, Van Zeveren A, Peelman LJ, (2007) PRNP polymorphisms associated with PRNP mRNA expression in blood in Belgian sheep population. – Prion 2007 congress Edinburgh, 26 - 28th September 2007.



Selection of oral presentations at international conferences in life sciences – as first author; title of abstract corresponds to title of presentation


  • Unified framework for epistasis detection in (un)relateds, ESHG 2009, Vienna, Austria

  • Explaining genetic heritability by interaction analysis? PHOEBE-P3G-BBMRI conference, Brussels, Belgium, 2009, - invited

  • Some perspectives on family-based GWAs, 55. Biom. Kolloquium 2009, Hannover, Germany, 2009 - invited

  • Perspectives on genomewide association screening in the light of epistasis, Scientific Symposium--New methodology for multi-factorial disease genetics, Malmö, Sweden, 2008 - invited

  • Genomic screening in family based association testing using the same data set and the multiple testing problem, 5th annual Hawaii international conference on statistics, mathematics and related fields, Honolulu, Hawaii, USA, 2006.

  • Genomic screening in family based association testing using the same data set and the multiple testing problem, 14th annual meeting of IGES, Park City, USA, 2005.

  • Genomic screening in family based association testing and the multiple testing problem, 3rd EMR-IBS conference, Greece, 2005.

  • Multicollinearity in prognostic factor analyses using the EORTC QLQ-C30: Identification and impact on model selection ISCB 2000, Italy, 2000.

  • Sensitivity Analysis of Longitudinal Binary Quality of Life Data with Dropout: An example using the EORTC QLQ-C30; ISCB-GMDS 99, Germany, 1999.

Selection of poster presentations at international conferences in life sciences – as first author or responsible author; title of abstract corresponds to title of presentation


  • MBMDR-2.6.2: an Efficient Software to Identify Significant Gene-Gene or Gene-Environment Interactions, PSIMEx Workshop: Interactions and Pathways. 28 March - 1 April 2011 - EMBL-EBI, Hinxton, UK (responsible author)

  • A detailed view on Model-Based Multifactor Dimensionality Reduction with quantitative traits for detecting gene-gene interactions: different ways of adjusting for lower-order effects, ESHG2011, Amsterdam, the Netherlands (responsible author)

  • A detailed view on model-based multifactor dimensionality reduction with quantitative traits for detecting gene-gene interactions: different ways of adjusting for lower-order effects, HGM2011, Dubai, UAE (responsible author)

  • Got heritability lost in a world of interactions? HGM2011, Dubai, UAE

  • Using mixed models with a mixture of normal distributions for the random residual effect leads to a fast and powerful genomewide association test, IBC, Florianopolis, Brasil, 2010 (responsible author)

  • A detailed view on model-based multifactor dimensionality reduction with quantitative traits for detecting gene-gene interactions: different ways of adjusting for lower-order effects, IBC, Florianopolis, Brasil, 2010 (responsible author)

  • Model-Based Multifactor Dimensionality Reduction for detecting gene-gene interactions in case-control data in the absence and presence of noise, ASHG, Washington, USA, 2010

  • Eelucidating the molecular etiology of asthma using genome-wide association study pathway analysis, ASHG, Washington , USA, 2010 (responsible author)

  • Model-Based Multifactor Dimensionality Reduction for detecting gene-gene interactions in case-control data in the absence and presence of noise, IGES, Boston, USA, 2010

  • Model-Based Multifactor Dimensionality Reduction to detect epistasis for quantitative traits in the presence of error-free and noisy data , IGES, Boston, USA, 2010 (responsible author)

  • Alternative risk cell definitions based on ranking improve performance of model-based multifactor dimensionality reduction for epistasis detection, IGES, Boston, USA, 2010 (responsible author)

  • A detailed view on several Model-Based Multifactor Dimensionality Reduction methods for detecting gene-gene interactions in case-control data in the absence and presence of noise, ECCB, Ghent, Belgium, 2010 (responsible author)

  • Model-Based Multifactor Dimensionality Reduction to detect epistasis for quantitative traits in the presence of error-free and noisy data, ECCB, Ghent, Belgium, 2010 (responsible author)

  • A family-based association test to detect gene-gene interactions in the presence of linkage (responsible author) IGES, Hawaii, 2009

  • Epistasis detection using MB-MDR, guided by prior biological knowledge (responsible author) IGES, Hawaii, 2009

  • Selecting multiple epistatic models using MB-MDR (responsible author). ASHG Annual Meeting, Hawaii, 2009

  • FAM-MDR: a novel multifactor dimensionality reduction method for interactions. UK-MEG2008, Barcelona, Spain, 2008.

  • MB-MDR based screening to detect high-order genetic interactions in (un-) related individuals. BBC2008, Maastricht, the Netherlands, 2008.

  • FAM-MDR: A flexible method of multifactor dimensionality reduction for high-order genetic interaction in related individuals, ASHG Annual Meeting, USA, 2008

  • Genomic screening methodology for common diseases and complex traits, accepted poster at the Third Seattle Symposium in Biostatistics – statistical genetics and genomics, Washington, USA, 2005.

  • Genomic screening in family-based association testing, IGES Annual Meeting, the Netherlands, 2004.

  • The Multivariate Dale Model and Genetic Associations, ASHG Annual Meeting, USA, 2002.

  • Merits of the Multivariate Dale Model in Genetic Association Studies, IGES Annual Meeting, USA, 2002.

  • Merits of the multivariate Dale model in genetic association studies, EMGM, UK, 2002.

  • Introduction of the Multivariate Dale Model in Genetic Association Studies, ASHG Annual Meeting, USA, 2001.

Announcements at other international and national scientific events


Publications other than articles


  • Arijs I, Van Lommel L, De Hertogh G, Machiels K, Lemaire K, Van Steen K, Van Assche G, Vermeire S, Schuit F, Rutgeerts P (2011) Mucosal gene expression profiling differentiates early from late ileal crohn’s disease – Belgian Week 2011 Acta Gastroenterol. Bel

  • Breynaert C, Ferrante F, Fidder H, Van Steen K, Noman M, Ballet V, Vermeire S, Rutgeerts P, Van Assche G (2011) Tolerability of shortened infliximab infusion times in patients with inflammatory bowel diseases: a single center cohort study – Belgian Week 2011 Acta Gastroenterol. Bel

  • Cleynen I, Van Moerkercke W, Vande Casteele N, Ballet V, Juergens M, Breynaert C, Drobne D, Vandecandelaere P, Gils A, Van Steen K, Noman M, Van Assche G, Rutgeerts P, Segaert S, Vermeire S (2011) Anti-tnf induced skin manifestations in ibd patients : characterization and search for predisposing factors. – Belgian Week 2011 Acta Gastroenterol. Bel

  • De Greef E, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paquot I, Alliet P, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier J F, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K and Veereman G for the IBD working group of the Belgian Society of Pediatric Gastroenterology, Hepatology and Nutrition (BeSPGHAN) and the Belgian IBD Research and Development (BIRD) (2011) Profile of belgian pediatric crohn disease (cd) patients: presentation and diagnostic features – Acta Gastro-Enterologica Belgica

  • De Greef E, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paquot I, Alliet P, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier J F, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K and Veereman G for the IBD working group of the Belgian Society of Pediatric Gastroenterology, Hepatology and Nutrition (BeSPGHAN) and the Belgian IBD Research and Development (BIRD) (2011) Profile of belgian pediatric crohn’s disease (cd) patients: associations between variables at diagnosis – Acta Gastro-Enterologica Belgica




  • Arijs I, Quintens R, Lemaire K, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P (2010). Intestinal mucosal gene expression of endothelial cell adhesion molecules in patients with inflammatory bowel disease before and after first infliximab treatment. Acta Gastro-Enterologica Belgica

  • Cleynen I, Mahachie John J.M, Henckaerts L, Van Moerkercke W, Rutgeerts PJ, Van Steen K, and Vermeire S (2010). Molecular Reclassification of Crohn’s Disease by cluster analysis of genetic variants. Acta Gastro-Enterologica Belgica




  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Quintens R, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P (2009) Colonic mucosal expression of barrier genes in patients with inflammatory bowel disease before and after first infliximab treatment. Acta Gastro-Enterologica Belgica.

  • Arijs I, Quintens R, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. (2009) The impact of infliximab therapy on colonic mucosal expression of barrier genes in patients with inflammatory bowel disease. Acta Gastro-Enterologica Belgica

  • Jürgens M, Schnitzler F, Van Steen K, Mahachie J, Ballet V, Noman M, Hoffman I, Van Assche G, Rutgeerts PJ, Vermeire S (2009). Predictive Value of C-Reactive Protein Level Changes On the Long Term Outcome of Infliximab in Crohn's Disease. Acta Gastro-Enterologica Belgica D17




  • Arijs I, Van Lommel L, Van Steen K, De Hertogh G, Ferrante M, Joossens M, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. (2008) Mucosal gene signatures to predict response to infliximab in patients with inflammatory bowel disease. Acta Gastro-Enterologica Belgica, 71: D33

  • M Joossens, V De Preter, K Van Steen, N Vermeulen, G Huys, K Verbeke, P Vandamme, P Rutgeerts, S Vermeire.( 2008) Long term stability of gut microbiota in Crohn’s disease patients compared to healthy relatives. Acta Gastroenterol Bel, 71: D73




  • Joossens M, Vanhoutte T, De Preter V, Van Steen K, Henckaerts L, Huys G, Verbeke K, Vandamme P, Rutgeerts P, Vermeire S (2007). Faecal bacterial DGGE profiles of Crohn’s disease patients are different from those of their healthy first degree relatives and matched healthy controls. Acta Gastroenterol. Bel,


Abstracts – no publication information available


  • Breynaert C, Ferrante F, Fidder H, Van Steen K, Noman M, Ballet V, Vermeire S, Rutgeerts P, Van Assche G (2011) Tolerability of shortened infliximab infusion times in patients with inflammatory bowel diseases: a single center cohort study – NVGE, Veldhoven, the Netherlands 2011

  • De Greef E, Hoffman I, Smets F, Van Biervliet S, Scaillon M, Hauser B, Paqout I, Alliet Ph, Arts W, Dewit O, Peeters H, Baert F, D’Haens G, Rahier J-F, Etienne I, Bauraind O, Van Gossum A, Vermeire S, Fontaine F, Muls V, Louis E, Van de Mierop F, Coche JC, Mahachie John JM, Van Steen K, Veereman G (2011) G Profil d’une population d’enfants et d’adolescents attaints de maladie de Crohn – GFGHNP de Liège




  • Arijs I, Quintens R, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. (2009) TECK and MADCAM-1 mucosal expression in active IBD: the effect of infliximab therapy - submitted for the National Cross-Disciplinary symposium on Immune Mediated Inflammatory Diseases 2009.

  • Arijs I, Quintens R, Van Lommel L, Van Steen K, De Hertogh G, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. (2009) TECK and MADCAM-1 mucosal expression in active IBD: the effect of infliximab therapy. Accepted for oral presentation at the National Cross-Disciplinary symposium on Immune Mediated Inflammatory Diseases, Dolce La Hulpe, March 13 - 14, 2009.

  • Cattaert T, Mahachie John JM, De Wit V, Van Steen K (2009) Selecting multiple epistatic models using MB-MDR –BVS 2009

  • Cattaert T, Mahachie John JM, Van Steen K (2009). Selecting multiple epistatic models using MB-MDR – submitted for BBC 2009

  • Cattaert T, Mahachie John JM, Van Steen K (2009). Selecting multiple epistatic models using MB-MDR – submitted for DYSCO 2009




  • Cattaert Tom, Urrea Victor, Calle Malu, De Wit Vanessa, Malats Nuria, Van Steen Kristel (2008) FAM-MDR: A method for genetic association studies with epistasis using families –DYSCO 2008




  • De Lobel L, Van Steen K, De Meyer H, (2007) Alternative methods to detect gene-gene interactions – 15th Annual meeting of the Belgian Statistical Society (BVS) Antwerp, 19-20 October 2007.




  • Wark PA, Souverein OW, Van Steen K, Van 'T Veer P, (2002) Onderzoeken van etiologische heterogeniteit van kanker met behulp van multinomiale logistische regressie. In: WEON (Werkgroep Epidemiologisch Onderzoek Nederland) 2002, Nijmegen, s.l.



Selection of oral presentations in life sciences; tile of abstract corresponds to title of presentation

  • Got genetic heritability lost in a world of interactions? University of Maastricht, MAASTRO, the Netherlands, 2011 - invited

  • Got genetic heritability lost in a world of interactions? University of Munich, Munich, Germany, 2010 - invited

  • Perspectives on Large-Scale Multi-Stage Family-Based Association Studies, UMCG Seminar Series May, Groningen, the Netherlands, 2010 - invited

  • From data to statistical analysis: Explaining genetic heritability by interaction analysis, INSERM, Paris, France, 2009 - invited

  • Multifactor dimensionality reduction methods: coping with epistasis, Montefiore seminar series (joint presentation with Tom Cattaert) ULg, Liège, Belgium, 2009 - invited

  • Interaction analysis in the context of GWAs, UMCG Seminar Series May, Groningen, the Netherlands, 2009 - invited

  • Screening strategies to detect genetic interactions and subphenotypes in
    (un)-related individuals, University Hospital Ghent, Medical Genetics, Ghent, Belgium, 2009 - invited

  • MB-MDR based screening strategies to detect high-order genetic interactions in (un)-related individuals, Institut für Medizinische Biometrie und Statistik, Universitaet zu Lübeck, Lübeck, Germany, 2009 - invited

  • MB-MDR based screening strategies to detect high-order genetic interactions in (un)-related individuals, University of Nantes (BIL seminar series) Nantes, France, 2008 - invited

  • The challenges of detecting epistatic patterns in genomic association studies, Klinikum Grosshadern, Germany, 2008 - invited

  • MB-MDR based screening strategies to detect high-order genetic 

  • interactions in (un-)related individuals, Institute of Epidemiology - Helmholtz Zentrum München (German Research Center for Environmental Health, Neuherberg) Germany, 2008 - invited

  • FAM-MDR, a novel screening method to detect epistasis in genetic association studies (Bio-Informatique Ligérienne) Nantes, France, 2008 - invited

  • MB-MDR based screening strategies to detect high-order genetic  interactions in (un-)related individuals, Imperial College, London, UK, 2008 - invited

  • MB-MDR based screening to detect high-order genetic interaction in (un-) related individuals, BBC 2008, Maastricht, the Netherlands, 2008 - invited

  • MB-MDR based screening strategies to detect high-order genetic interactions in (un-)related individuals, NCIO, Madrid, Spain, 2008 - invited

  • MB-MDR based screening strategies to detect high-order genetic  interactions in (un-)related individuals, Helmholtz Zentrum München, Munich, Germany, 2008 - invited

  • Unravelling the mysteries of genetic interactions
    – The semi-parametric way? –, ERS-GA2len Research Seminar : "Post Genome Respiratory Epidemiology II: An Interdisciplinary Challenge", Cernay, France, 2008 - invited

  • Statistical Challenges in Genomewide Association Analysis, ERS-GA2len Research Seminar : "Post Genome Respiratory Epidemiology II: An Interdisciplinary Challenge", Cernay, France, 2008 - invited

  • FAM-MDR: A family-based multifactor dimensionality reduction technique to detect gene-gene interactions, Harvard School of Public Health, Boston, USA - invited

  • Detecting high-order interactions – the semi-parametric way?, Universitat Politècnica de Catalunya (UPC) Barcelona, Spain, 2008 - invited

  • Statistical challenges in genomewide association analysis, Universitat de Vic, Vic, Spain, 2008 - invited

  • A statistical genetics research club …, VIB Technology Park Ghent, Ghent, Belgium, 2008 - invited

  • Power in statistical genetics and statistical significance; Part II: Evaluating power in genomewide association studies, Complex Genetics Meeting Seminar – Statistical Genetics Research Club, UZ Gasthuisberg, Leuven, Belgium, 2008 - invited

  • Power in statistical genetics and statistical significance; Part I: What it involves and does not involve (Peter Konings and Kristel Van Steen) Complex Genetics Meeting Seminar – Statistical Genetics Research Club, UZ Gasthuisberg, Leuven, Belgium, 2008 - invited

  • Statistical perspective on genomewide screening, Kick-off Meeting - Statistical Genetics Research Club, Montefiore, ULg, Liège, Belgium, 2008 - invited

  • True or false – when the number of SNPs grows, Mc Master University, Hamilton, USA, 2008 - invited

  • Invitation by Prof Dr Judah Denburg to attend AllerGen’s 3rd annual research conference in Alberta Canada – discussant panel member as former GA2LEN affiliate and scientific collaborator with birth cohorts work package, 2008. - invited

  • Unravelling the mysteries of genetic interactions – a statistical challenge, Liège, Belgium, 2007 - invited

  • Unravelling the mysteries of genetic interactions – a statistical perspective (Invited Speaker) Lausanne, Switzerland, 2007 - invited

  • Are we ready for genomewide association analysis? Quality of Life Unit
    Mediterranean Institute of Hematology (IME) (Invited Speaker) Rome, Italy, 2007. - invited

  • Genomic Complex, simplex, complexity and simplicity in statistical genetics (Invited speaker) Oncologisch Zorgprogramma UZ Ghent (Invited Speaker) UZ Ghent, Belgium, 2007 - invited

  • Perspectives on genomic association screening, Invited Seminar, UCL, Louvain-la-Neuve, Belgium, 2007. - invited

  • Are we ready? Invited Speaker, UMC, Utrecht, The Netherlands, 2007 - invited

  • Perspectives on genomic screening,Invited Seminar, ESAT - KUL, Leuven, Belgium, 2007. - invited

  • Statistical Consulting for the Clinic (Provisional title; Invited Speaker) UZ Ghent Biostatistics Workshop, Ghent, Belgium, 2007. - invited

  • Topics in Genetic Association Analysis (Invited Speaker) UCL, Belgium, 2007.

  • When the number of SNPs grows too large, Universitat Politècnica de Catalunya (UPC) Barcelona, Spain, 2006. - invited

  • When the number of SNPs grows, part II, Seminar Series on Complex Genetics, University Hospital Gasthuisberg Leuven, Belgium, 2006. - invited

  • When the number of SNPs grows, part I, Seminar Series on Complex Genetics, University Hospital Gasthuisberg Leuven, Belgium, 2006. - invited

  • Genomewide association screening using family-based association tests, Seminar at the faculty of Medicine at UZ Gasthuisberg (Afdeling Hypertensie en Cardiovascularie Revalidatie) Leuven, Belgium, 2006. - invited

  • Genomic screening methodology for common diseases and complex traits, Organon, Oss, the Netherlands, 2006. - invited

  • Perspective on genomic screening in families, Invited Seminar, ESAT - KUL, Leuven, Belgium, 2006. - invited

  • Genomic Screening in Family Based Association Testing using the same Data, Invited research stay with talk at the Institute Municipal d’Investigacio Medica (IMIM) Barcelona, Spain, 2006. - invited

  • Genomic screening in family based association testing using the same data set and the multiple testing problem, IAP Workshop V on “Flexible statistical analysis adapted to complex data structures”, UCL, Louvain-la-Neuve, Belgium, 2006. - invited

  • Genomic screening in family based association testing using the same data set and the multiple testing problem, Seminars in econometrics and statistics (invited speaker) Faculty of econometrics and applied economics, University Center for Statistics, KULeuven, Leuven, Belgium, 2006. - invited

  • Key concepts in genetic epidemiology, Seminars in epidemiology and clinical trials (invited speaker) Working group on epidemiology and center for clinical pharmacology, UZ St Rafael, Leuven, Belgium, 2006. - invited

  • Genomic screening methodology for common diseases and complex traits, CMGG Invited Seminars, University Hospital Ghent, Belgium, 2006. - invited

  • Genomic screening methodology for common diseases and complex traits, Seminar Series on Complex Genetics (Invited Speaker) Department of Psychiatry, University Hospital Gasthuisberg Leuven, Belgium, 2006. - invited

  • Genomic screening in family based association studies, Channing Laboratory FBAT seminar series, Harvard Medical School, USA, 2004. - invited

  • Genomic screening in family based association testing using PBAT, Invited talk at the department of molecular genetics (UA) organized by VIB-UA, Belgium, 2004. - invited

  • Exhaustive allelic transmission disequilibrium tests based on TDT, Channing Laboratory FBAT seminar series, Harvard Medical School, USA, 2004.

  • Statistical methods in psychiatric genetics, Pychiatric Biostatistics Seminar Series, Harvard School of Public Health, USA, 2003. - invited

  • Comparing DNA sequences using generalized estimating equations and pseudo-likelihood, Hasselt University Seminar Series, Belgium, 2002. - invited

  • Genetic associations using the multivariate Dale model, 3 Country Corner (3CC) Meeting, Belgium, 2002.

  • The multivariate Dale model and genetic associations, Channing Laboratory FBAT seminar series, Harvard Medical School, USA, 2002. - invited

  • The multivariate Dale model and genetic associations, invited talk at Department of Epidemiology, Harvard School of Public Health, USA, 2002. - invited

  • An introduction into the genetic vocabulary (Part 1-4) Research forum Hasselt University, Belgium, 2001.

  • The omnipresence of missingness in statistical genetics. Research forum Hasselt University- tUL, Belgium, 2001. - invited

  • Multiple imputation in practice, Research forum Hasselt University, Belgium, 2000. - invited

  • Analyzing longitudinal quality of life data with dropout; a macro oriented approach (Part 1-4) EORTC Seminar Series, Belgium, 1999. - invited

  • Estimation of genetic distances using statistical distance measures, University of Newcastle - school of mathematics and statistics, UK, 1998. – invited

Selection of poster presentations in life sciences – as first or responsible author; title of abstract corresponds to title of presentation


  • Selecting multiple epistatic models using MB-MDR (responsible author). BVS annual meeting, Lommel, Belgium, 2009

  • The omnipresence of missingness in statistical genetics – an equivalence test to compare DNA sequences, 1st Dutch-Belgian Biometric Conference (BBC2001) Belgium, 2001.






  1. Scientific networking


To Montefiore (ULg) invited guests





Speaker

Affiliation

Date

Location

Description

Workshop

K Van Steen (moderator)

Montefiore, ULg, Belgium

02/02/2011

ULg

Joint meeting of UA, CHU and Montefiore research teams: exploring common grounds




Jean-Charles Lambert

Institut Pasteur de Lille, France

28/01/2011

ULg

Genetics of Alzheimer’s disease

Conference with short course :

Capita Selecta in Complex Disease Analysis (CSCDA2010)

www.statgen.be




25-27/08/2010

Leuven City

1st Edition of biennial Conference organized by ULg, in collaboration with 1 extra university in Wallonia and 2 universities in Flanders




Rudy Parker

Golden Helix, Inc, USA

24/08/2010

ULg / GIGA

Golden Helix features for CNV GWAS and Imputation efforts




P Konings

ESAT, Leuven, Belgium

28/05/2010

ULg

Fast computing in R and beyond




K Van Steen

Montefiore, ULg, Belgium

12/05/2009

KUL

Evaluation of the Statistical Genetics Research Club : Research and Discussion Meeting




B Müller-Myhsok

Max-Planck-Institute of Psychiatry, Munich, Germany

02/07/2009

ULg

Novel techniques in statistical genetics




Y Aulchencko

Erasmus MC Rotterdam, Rotterdam, the Netherlands

23/03/2009

ULg

Pedigree-based association testing

Summer Sabbatical at Montefiore – Ulg (Belgium)

A Ziegler

Universitaet zu Luebeck, Luebeck, Germany

21/11/2008

ULg

Gene-gene and gene-environment interactions




L-C Tranchevent

ESAT, KUL, Leuven, Belgium

18/11/2008

ULg

Gene prioritization
(includes session with bioinformatics students ULg about the software ENDEAVOUR)


Conference with short course: Statistics in Genetics

www.statgen.be




15-18/09/2008

ULg

Co-organized by K Van Steen (Montefiore) and G Haesbroeck (Département de mathématique  /  Statistique mathématique)

Subsides aux écoles doctorales thématiques (département des Sciences de la Vie ; département des sciences biomédicales et précliniques ; département d’astrophys, géophysique et océanographie ; département des sciences de la santé)






G de Cooman

SYSTeMS Research Group, UG, Ghent, Belgium

12 /08/2008

ULg

Trying to be more honest about probabilistic modelling : a case study involving Markov chains




H Van Maldeghem

Pure mathematics and computer science, UG, Ghent, Belgium

18/04/2008

ULg

From real estate denomination to pure mathematics and back to real life

Kick-off Meeting Statistical Genetics Research Club (www.statgen.be)

K Van Steen (Montefiore) and G Haesbroeck (Département de mathématique  /  Statistique mathématique)




08/04/2008

ULg

Setting goals and aims 

This research club aims to bring together people from different backgrounds, within Life Sciences, so as to stimulate discussions and provide a nutrient pool for growing novel and cutting-edge ideas in the field of statistical genetics.




Achieving the goals

  • by organizing introductory sessions to establish a common language

  • by hosting seminars with state-to-the-art approaches

  • by reading, presenting and discussing key papers, from conception of ideas to current common practice, to "grow" into a problem area


Club House

  • Institut Montefiore / Bioinformatique (at ULg)

  • Services de Statistique de l'Institut de Mathématique (at ULg)



See alsoCompetence:Networks”





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  • Van Steen K
  • Van Steen
  • Van Steen Kristel
  • Conference with short course : Capita Selecta in Complex Disease Analysis (CSCDA2010)
  • Conference with short course: Statistics in Genetics
  • Kick-off Meeting Statistical Genetics Research Club (www.statgen.be)

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